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	Provedor de dados Arq. Bras. Med. Vet. Zootec. (1) Autor Bessa,L.R.G. (1) Cândido,A.L. (1) Leite,R.C. (1) Resende,M. (1) Palavra-chave Bovine herpesvirus-1.2a (1) DNA vaccine (1) ELISA (1) Glycoprotein D gene (1) Tipo do documento Info:eu-repo/semantics/article (1) Ano 2003 (1) País Brazil (1) Idioma Inglês (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 1 Primeira ... 1 ... Última Serological responses in sheep injected with plasmids encoding bovine herpesvirus 1 (BHV-1) gD glycoprotein Arq. Bras. Med. Vet. Zootec. Cândido,A.L.; Resende,M.; Bessa,L.R.G.; Leite,R.C.. A genetic vaccine consisting of the bovine herpesvirus-1.2a (BHV-1.2a) glycoprotein D (gD) gene under the control of the cytomegalovirus immediate-early promoter/enhancer was generated and administered to sheep intramuscularly in the neck. All animals developed serum antibodies which recognized the homologous antigen (BHV-1.2a strain BH-83) and also exhibited cross-reactivity against the heterologous antigen (BHV-5 strain EVI-190). Three intramuscularly injections were given but serological responses were not improved after the second inoculation. Specific antibodies were detected against BHV-1.2a until at least 12 months after the first inoculation. However, the capacity to induce antibodies against BHV-5 was lower and of shorter duration than to BHV-1.2a. Tipo: Info:eu-repo/semantics/article Palavras-chave: Bovine herpesvirus-1.2a; Glycoprotein D gene; DNA vaccine; ELISA. Ano: 2003 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352003000300002 Registros recuperados: 1 Primeira ... 1 ... Última

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